Try the given below methods to resolve Cannot Start Microsoft Outlook. Cannot open the outlook window. The set of folders cannot be opened issue:


Method 1:

Try opening Outlook in safe mode and check. Follow the steps:

1. Press “Windows” Key + “R” (combine)

2. Type “Outlook.exe /safe” (leave a space after Outlook) >> Click on “OK” button.


If  you are able to open Microsoft Outlook in safe mode without any error, refer the following steps on how to disable the add-ins from Outlook:

1. Open “Microsoft Outlook”.

2. Go to “File” tab >> “Options” >> “Add-Ins”.

3. Select “Com Add-ins” >> Click on “GO”.

4. Uncheck the available Add-ins >> Click on “OK” button.


Once the keys you have deleted the add-ins keys, Open Outlook and check if it works fine.


Method 2:

If the above steps do not resolve the issue, then try creating a new profile in Outlook if and check if it is working. Refer the link on How to create a new profile:

https://support.microsoft.com/en-us/kb/829918


Method 3:

Last but not the least Inbox Repair Tool (scanpst.exe), you should run scanpst.exe utility to repair minor level corruption.


Method 4:

Check if Outlook is running in compatibility mode.

Compatibility mode is designed to help a program run on an older operating system. If Outlook is running in compatibility mode, you can turn that off and see if it fixes the problem.

https://support.office.com/en-us/article/I-can-t-start-Microsoft-Outlook-2016-2013-or-2010-or-receive-the-error-Cannot-start-Microsoft-Office-Outlook-Cannot-open-the-Outlook-Window-d1f69da6-b333-4650-97bf-4d77bd7abb85


Method 5

Remove the Outlook Profile: https://support.microsoft.com/en-us/kb/829918

and exectue an Office Repair: https://support.office.com/en-us/article/Repair-an-Office-application-7821d4b6-7c1d-4205-aa0e-a6b40c5bb88b  



Note:

There is also an informative article on Cannot Start Microsoft Outlook while searching over the internet about your occurred issue.